Fracture Non-Union & Delayed Bone Healing
A fracture is considered a "delayed union" when it's healing more slowly than expected, and a "non-union" when healing has effectively stopped, typically defined as no meaningful progress on imaging for several months. This is a more specialized situation than most conditions on this site, and it requires close coordination with the orthopedic surgeon or physician managing your fracture. High-energy focused shockwave therapy is one of the more established non-surgical options studied for delayed and non-union fractures, with evidence including a randomized trial published in the Journal of Bone and Joint Surgery.
Common Symptoms
- Persistent pain or tenderness at a fracture site well beyond the typical healing timeline
- Continued movement or instability at the fracture site
- Imaging (X-ray or CT) showing incomplete bridging of the bone, or a visible gap, months after the injury
- Swelling that doesn't fully resolve as expected during normal healing
- A fracture site that remains painful with weight-bearing or use long after a comparable injury would typically have healed
Why It Happens
Most fractures heal on a predictable timeline as the body forms new bone across the break. Delayed union and non-union happen when that process stalls — due to factors like inadequate blood supply to the fracture site, excessive motion at the fracture during healing, infection, smoking, certain medications, diabetes, or simply the fracture's location and pattern. High-energy shockwaves are thought to stimulate the same mechanobiological healing signals (growth factor release, new blood vessel formation, stem cell recruitment) that a properly healing fracture would generate on its own.
Why It Can Become Persistent
Once healing has genuinely stalled — a true non-union rather than a fracture that's simply healing slowly — it typically will not resolve with more time or rest alone; the biological healing process needs to be actively restarted, which is why non-unions are usually addressed with a specific intervention (revision surgery, bone grafting, or in appropriate cases, shockwave therapy) rather than continued waiting.
Who Commonly Gets It
This affects people who've had fractures at locations with an inherently lower healing rate — including the scaphoid (wrist), fifth metatarsal (foot), tibia (shin), humerus (upper arm), and clavicle (collarbone) — as well as people with risk factors that slow bone healing generally, such as smoking, diabetes, certain medications, or a fracture with significant gapping or instability from the start.
How It Is Usually Diagnosed
Non-union and delayed union are diagnosed by the physician managing your fracture care, based on serial X-rays or CT imaging showing a lack of healing progress over an expected timeframe (commonly around 3 months for delayed union, 6-9 months for non-union, though definitions vary by bone and fracture type), combined with your symptoms and exam findings.
Traditional Treatment Options
- Continued immobilization/bracing: Sometimes extended if healing is progressing slowly but not stalled.
- Bone stimulator devices: Low-intensity ultrasound or electromagnetic bone growth stimulators are a non-invasive option for some delayed unions.
- Revision surgery with bone grafting: Surgically re-fixing the fracture and adding bone graft material is the traditional, well-established treatment for an established non-union.
- Addressing underlying risk factors: Smoking cessation, optimizing nutrition, and reviewing medications that may impair healing.
Why Someone Might Start Looking for Another Option
Revision surgery is effective but is still a surgery — with its own recovery time, risks, and cost — and some patients either aren't good surgical candidates or want to understand non-surgical options before committing to another operation, especially for a fracture that's already been through one surgical procedure.
Where Shockwave Therapy May Fit
High-energy focused extracorporeal shockwave therapy has a genuine, independently published evidence base specifically for delayed union and non-union fractures, including a randomized controlled trial in the Journal of Bone and Joint Surgery comparing shockwave therapy with surgical screw fixation for non-union fifth metatarsal fractures, and additional published research on humeral non-unions and the broader mechanism of shockwave-assisted bone repair. This is a more specialized application than most conditions on this site, and it's only appropriate with close coordination between our practice and the physician managing your fracture.
How Shockwave Treatment Works for This Area
Focused shockwaves are directed precisely at the fracture site under guidance appropriate to the bone involved, aiming to restart the biological signals associated with bone healing. This requires your prior fracture imaging and, in most cases, direct communication with your treating orthopedic surgeon before treatment is considered.
What the Treatment Feels Like
Treatment directly over a fracture site is often more intense than shockwave therapy for soft-tissue conditions, and your provider will discuss energy level, positioning, and what to expect based on the specific bone and fracture involved.
What Happens During Your First Visit
Your visit begins with a provider evaluation focused on your history and a physical exam relevant to your complaint. If shockwave therapy is determined to be clinically appropriate, your first treatment can typically be provided the same visit. See our What to Expect page for the full walkthrough.
New Patient Offer
New Patient Exam + First Treatment — $99
First treatment provided when clinically appropriate following your examination.
Who May Not Be Appropriate
- Anyone who has not had the diagnosis of delayed union or non-union confirmed by the physician managing their fracture
- Fractures with significant ongoing instability, large bone gaps, or infection, which typically need surgical management
- Active infection at or near the fracture site
- Certain circulatory, neurological, or bleeding-related conditions, per your provider's screening
- Pregnancy, in the treatment area, unless specifically cleared by your provider
This list is not exhaustive. Your provider will screen for contraindications during your evaluation.
Frequently Asked Questions
There's real, independently published evidence for high-energy shockwave therapy in delayed union and non-union fractures, including a randomized trial comparing it with surgical screw fixation for certain foot fractures. It's not appropriate for every non-union, though — factors like significant instability, large bone gaps, or infection typically still require surgery. This decision is made together with the orthopedic surgeon managing your fracture, not independently of them.
Both aim to restart stalled bone healing non-surgically, but they use different energy types (focused acoustic shockwaves vs. ultrasound or electromagnetic fields) and have different, separate evidence bases. Your provider can discuss which, if either, fits your specific fracture.
Yes. Non-union and delayed union are diagnosed and staged by the physician managing your fracture, and treatment planning for this specific condition is coordinated with them — this isn't a self-referred, walk-in evaluation the way a chronic tendon pain complaint might be.
What Research Says
Selected sources relevant to fracture non-union. See the full Research Center for our complete source registry and methodology.
The Journal of Bone and Joint Surgery (American) · 2010 · Furia, Juliano, Wade, Schaden, Mittermayr
This randomized trial compared high-energy extracorporeal shockwave therapy with intramedullary screw fixation (surgery) for nonunion of proximal fifth metatarsal (Jones-type) fractures and found comparable healing outcomes between the two approaches, with shockwave therapy avoiding surgical risks.
Limitations: This trial is specific to one fracture location and pattern (proximal fifth metatarsal nonunion); results should not be generalized to every non-union location or fracture type without individualized evaluation by the treating surgeon.
Injury · 2021 · Mittermayr, Haffner, Feichtinger, Schaden
This review summarizes the mechanobiology behind shockwave-stimulated bone repair and the published clinical evidence for extracorporeal shockwave therapy in delayed union and non-union fractures, concluding that ESWT is a valuable, efficient, and cost-effective intervention with healing rates comparable to surgical revision in appropriate cases.
Limitations: As a review by authors closely associated with shockwave bone-healing research, it should be read alongside independently conducted trials (such as the Furia et al. randomized trial cited alongside it) rather than as a stand-alone, fully independent assessment.
European Journal of Trauma and Emergency Surgery · 2022 · Dahm, Feichtinger, Vallant, Haffner, Schaden, Fialka, Mittermayr
This retrospective study evaluated high-energy shockwave therapy for delayed and non-union fractures of the humerus (upper arm bone), reporting favorable healing outcomes for a substantial proportion of patients treated non-surgically.
Limitations: Retrospective, uncontrolled design without a comparison group, and specific to humeral fractures — outcomes for other bones or fracture patterns may differ.
Foot & Ankle International · 2023 · Ramon, Lucenteforte, Alentorn-Geli, Steinbacher, et al.
This pilot study in soccer players compared shockwave treatment with surgery for proximal fifth metatarsal (Jones-type) stress fractures using the OrthoGold 100 device, evaluating healing and return-to-play outcomes between the two approaches.
Limitations: Described by its own authors as a pilot study — a smaller sample intended to inform future, larger trials rather than to be conclusive on its own — and specific to this one fracture location in athletes.
Journal of Clinical Medicine · 2022 · Mittermayr, Haffner, Eder, Flatscher, Schaden, Slezak, Slezak
This retrospective study of 49 compromised clavicle (collarbone) fractures compared focused shockwave therapy with surgery and found comparable 6-month healing rates between the two approaches (75% vs. 71%), with the shockwave group experiencing no serious complications versus several in the surgery group.
Limitations: Retrospective, non-randomized comparison (not a randomized trial), which carries a risk of selection bias — patients weren't randomly assigned to shockwave therapy versus surgery — and this is a single-center study.
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